What does MyRisk primarily detect?

• A. Hereditary cancer mutations
• B. Environmental risk factors
• C. Somatic mutations in tumors
• D. Lifestyle risk factors

Answer: (A)

MyRisk is designed to identify inherited germline variants that predispose a person to cancer, meaning mutations present in the DNA of every cell and passed through families. It tests germline DNA (such as from blood) to find pathogenic variants in cancer susceptibility genes, and the results inform surveillance and risk-reduction decisions for the patient and relatives. It does not detect somatic mutations that arise only in tumor tissue, which require tumor sequencing, and it does not measure environmental exposures or lifestyle factors, which are not detected by genetic testing. Therefore, it primarily detects hereditary cancer mutations.