How many genes are included in the MyRisk test?

• A. 63 genes
• B. 50 genes
• C. 100 genes
• D. 25 genes

Answer: (A)

A broad hereditary cancer panel like MyRisk is designed to detect pathogenic variants across a wide set of genes that contribute to inherited cancer risk. The version most commonly used includes 63 genes, spanning high-penetrance genes such as BRCA1 and BRCA2 and many others involved in breast, ovarian, colorectal, endometrial, pancreatic, and prostate cancer predisposition. This breadth increases the chance of identifying an inherited risk, guides individualized screening and risk-reduction plans, and can influence treatment options in some contexts. Panels are updated over time as new evidence emerges, so the exact gene count can change, but this version reflects a comprehensive scope. The other options would imply panels that are notably smaller or larger than this current comprehensive set, which would miss or overextend the intended gene coverage.